Alternative approach:
With the constraint that complementary events are to be avoided, I feel that the method used in the answer of aschepler is best. An alternative method is Inclusion-Exclusion. See this article for an
introduction to Inclusion-Exclusion.
Then, see this answer for an explanation of and justification for the Inclusion-Exclusion formula.
Let :
$~S_1~$ denote the set of all 5 card poker hands that contain the Ace of Spades.
$~S_2~$ denote the set of all 5 card poker hands that contain the Ace of Hearts.
$~S_3~$ denote the set of all 5 card poker hands that contain the Ace of Diamonds.
$~S_4~$ denote the set of all 5 card poker hands that contain the Ace of Clubs.
Note that in each of the four sets above, some of the elements in that set will represent a poker hand that contains more than one Ace.
The probability may be expressed as
$$\frac{N}{D} ~: ~~~D = \binom{52}{5}, ~~~N = | ~S_1 \cup S_2 \cup S_3 \cup S_4 ~|. \tag1 $$
So, the problem reduces to computing $~N,~$ as expressed on the RHS of (1) above.
Let $~T_1~$ denote $~|S_1| + |S_2| + |S_3| + |S_4|.$
For $~r \in \{2,3,4\},~$ let $~T_r~$ denote
$\displaystyle \sum_{1 \leq i_1 < i_2 < \cdots < i_r \leq 4} | ~S_{i_1} \cap S_{i_2} \cap \cdots \cap S_{i_r} ~|.$
That is, $~T_r~$ represents the sum of $~\displaystyle \binom{4}{r}~$ terms.
Then, in accordance with Inclusion-Exclusion theory,
$$N = | ~S_1 \cup S_2 \cup S_3 \cup S_4 ~| = \sum_{r=1}^4 (-1)^{r+1} T_r. \tag2 $$
So, the entire problem has been reduced to computing $~T_r ~: ~r \in \{1,2,3,4\}.$
$\underline{\text{Computation of} ~T_1}$
$~S_1~$ represents all poker hands that contain the Ace of Spades.
Therefore, $~\displaystyle |S_1| = \binom{51}{4}.$
By considerations of symmetry,
$~|S_1| = |S_2| = |S_3| = |S_4|.$
Therefore,
$$T_1 = \binom{4}{1} \times \binom{51}{4}.$$
$\underline{\text{Computation of} ~T_2}$
$~S_1 \cap S_2~$ represents all poker hands that contain both the Ace of Spades and the Ace of Hearts.
Therefore, $~\displaystyle |S_1 \cap S_2| = \binom{50}{3}.$
By considerations of symmetry,
for $~1 \leq i_1 < i_2 \leq 4,$
$~|S_{i_1} \cap S_{i_2}| = |S_1 \cap S_2|.$
Therefore,
$$T_2 = \binom{4}{2} \times \binom{50}{3}.$$
$\underline{\text{Computation of} ~T_3}$
$~S_1 \cap S_2 \cap S_3~$ represents all poker hands that contain the Ace of Spades, the Ace of Hearts, and the Ace of Diamonds.
Therefore, $~\displaystyle |S_1 \cap S_2 \cap S_3| = \binom{49}{2}.$
By considerations of symmetry,
for $~1 \leq i_1 < i_2 < i_3 \leq 4,$
$~|S_{i_1} \cap S_{i_2} \cap S_{i_3}| = |S_1 \cap S_2 \cap S_3|.$
Therefore,
$$T_3 = \binom{4}{3} \times \binom{49}{2}.$$
$\underline{\text{Computation of} ~T_4}$
$~S_1 \cap S_2 \cap S_3 \cap S_4~$ represents all poker hands that contain all four Aces.
Therefore,
$$T_4 = |S_1 \cap S_2 \cap S_3 \cap S_4| = \binom{48}{1}.$$
$\underline{\text{Final Computation}}$
The probability is
$$\frac{N}{D} ~: ~D = \binom{52}{5}.$$
$$N = \sum_{r=1}^4 (-1)^{r+1} T_r = \sum_{r=1}^4 (-1)^{r+1} \binom{4}{r} \binom{52-r}{5-r}.$$