It may interest the reader that this sum can be evaluated using the
technique of annihilated coefficient extractors (ACE).
Start with
$$q_n = \sum_{k=1}^n (-1)^k \times (k-1)! \times
{n-1 \brace k-1} \times \sum_{j=0}^{k-1} H_j$$
and introduce the generating function
$$Q(z) = \sum_{n\ge 1} q_n \frac{z^{n-1}}{(n-1)!}.$$
Recall the bivariate generating function of the Stirling numbers of
the second kind which is
$$G(z, u) = \exp(u(\exp(z)-1)).$$
Substitute this into $Q(z)$ to get
$$\sum_{n\ge 1} \frac{z^{n-1}}{(n-1)!}
\sum_{k=1}^n (-1)^k \times (k-1)! \times
(n-1)! [z^{n-1}] \frac{(\exp(z)-1)^{k-1}}{(k-1)!} \times
\sum_{j=0}^{k-1} H_j.$$
This immediately simplifies to
$$\sum_{n\ge 1} z^{n-1}
\sum_{k=1}^n (-1)^k \times
[z^{n-1}] (\exp(z)-1)^{k-1} \times
\sum_{j=0}^{k-1} H_j.$$
Switch summations to obtain
$$\sum_{k\ge 1} (-1)^k \times
\sum_{j=0}^{k-1} H_j \times
\sum_{n\ge k} z^{n-1} [z^{n-1}] (\exp(z)-1)^{k-1}.$$
The inner sum contains the promised annihilated coefficient
extractor and everything simplifies to
$$\sum_{k\ge 1} (-1)^k \times
\sum_{j=0}^{k-1} H_j \times (\exp(z)-1)^{k-1}.$$
Switch sums one more time to obtain
$$\sum_{j\ge 0} H_j \sum_{k\ge j+1} (-1)^k (\exp(z)-1)^{k-1}$$
which is
$$- \sum_{j \ge 0} H_j \frac{(1-\exp(z))^j}{1-(1-\exp(z))}
= - \exp(-z) \sum_{j\ge 0} H_j \times (1-\exp(z))^j.$$
Now ask when the term $1/q$ occurs in the harmonic number $H_j =
\sum_{q=1}^j 1/q$ to obtain
$$- \exp(-z) \sum_{q\ge 1}
\frac{1}{q} \sum_{j\ge q} (1-\exp(z))^j.$$
This is
$$- \exp(-z) \sum_{q\ge 1}
\frac{1}{q} \frac{(1-\exp(z))^q}{1-(1-\exp(z))}
= - \exp(-2z) \sum_{q\ge 1}
\frac{1}{q} (1-\exp(z))^q
\\ = - \exp(-2z)
\log\frac{1}{1-(1-\exp(z))}
= z \times \exp(-2z).$$
We are done and we may conclude by extracting coefficients to find
$$q_n = (n-1)! [z^{n-1}] \quad z \times\exp(-2z)
= (n-1)! [z^{n-2}] \exp(-2z) \\
= (n-1)! \times \frac{(-1)^{n-2} 2^{n-2}}{(n-2)!}
= (-1)^n \times (n-1) \times 2^{n-2}.$$
This is indeed OEIS A001787 up to signs:
$$0, 1, 4, 12, 32, 80, 192, 448, 1024, 2304, 5120, 11264, 24576,\ldots$$
There is another computation with annihilated coefficient extractors at this
MSE link.