First, it's important to note that if $AB = I_4$, then (since $A,B$ are square matrices) we have $B = A^{-1}$ and $A = B^{-1}$, which is to say that
$$
AB = BA = I_4.
$$
For more on that, see this post.
Let's go through the first problem. We are trying to show that $Ax_1,\dots,Ax_5$ span $\Bbb R^4$. By definition, that means the following:
For any vector $b \in \Bbb R^4$, there exist coefficients $c_i$ such that $c_1 Ax_1 + \cdots + c_5 Ax_5 = b$.
With that in mind, we can construct the proof as follows. Begin with a vector $b \in \Bbb R^4$; our goal will be to show that satisfactory coefficients $c_i$ exist. Before writing a formal proof, it is useful to note that
$$
c_1 Ax_1 + \cdots + c_5 Ax_5 = b \iff\\
A[c_1 x_1 + \cdots + c_5 x_5] = b \iff\\
c_1 x_1 + \cdots + c_5 x_5 = A^{-1}b
$$
That is, we have come to the following insight: if there exist coefficients such that $c_1 x_1 + \cdots + c_5 x_5 = A^{-1}b$, then these same coefficients will satisfy $c_1 Ax_1 + \cdots + c_5 Ax_5 = b$, which is ultimately what we want.
Thus, one proof would be as follows: argue that there exist coefficients $c_i$ for which $c_1 x_1 + \cdots + c_5 x_5 = A^{-1}b$ (how do we know that this is true?). Then, present the series of equations above to conclude that these coefficients also satisfy $c_1 Ax_1 + \cdots + c_5 Ax_5 = b$. Because $b$ was an arbitrary vector in $\Bbb R^4$, this is exactly the conclusion we want: the vectors $Ax_1,\dots,Ax_5$ span $\Bbb R^4$.
If we want to avoid the result that I refer to in the beginning (desirable in the infinite-dimensional case for instance), then the problem is a bit trickier but the idea is essentially the same.
First, select $c_1,\dots,c_5$ such that
$$
c_1x_1 + \cdots + c_5 x_5 = Bb.
$$
Now, multiply both sides of the equation (from the left) by $A$ to find that
$$
A(c_1x_1 + \cdots + c_5 x_5) = A(Bb) \implies\\
c_1(Ax_1) + \cdots + c_5(Ax_5) = (AB)b \implies\\
c_1(Ax_1) + \cdots + c_5(Ax_5) = b
$$
so that once again, we can conclude that $Ax_1,\dots,Ax_5$ spans $\Bbb R^4$.