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There is a nice proof on MSE which shows that for $n \ge 1$, $$ \sum_{k = 0}^{n}{4n \choose 4k} = {1 \over 4}\left[\left(-1\right)^{n}\, 2^{2n + 1} + 16^{n}\right] $$

I wonder if there is a more combinatorial proof for this?

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