If $S$ is a compact surface then one needs at least two parametrizations to cover $S$
My try
I reason by contradiction. Suppose $X:U \to S$ is a parametrization that covers $S$, so that $X$ is an homeomorphism. The only argument I can think of uses that $U$ is open and $S$ is compact so that these sets can't be isomorphic because a compact set cannot be isomorphic to an open set.
In other to precise this claim I saw this question where they claim:
A non-empty open subset of $\mathbb{R}^n$ is never compact.
Perhaps I am being silly, but what is the formal justification of this fact?