Recently I've tackled the Putnam 2005 A5 integral, that is, $\displaystyle\int_{0}^{1}\frac{\ln(x+1)}{x^2+1}\mathrm{d}x$. In solving this, I converted it to multiple integrals- I used a $u$ substitution to show it was equal to $\displaystyle\int_{0}^{\frac{\pi}{4}}\ln(\sin{x}+\cos{x})-\ln(\cos{x})~\mathrm{d}x$. This enabled me to make a symmetry argument and it allowed me to finally solve it.
This made me wonder, does converting an integral into multiple always make it easier to solve? This is the central idea of partial fractions. This integral also finally simplified once I converted it into multiple integrals. Do pretty much all integrals become easier, or at least not harder, after making them into multiple integrals?