This kind of confusion is very prevalent and the primary reason behind the confusion is the wrong definition of definite integral as area under a curve.
It is important to first understand that the definition of symbol $\int_{a}^{b}f(x)\,dx$ has nothing do with area as such. The definition has to be based on numbers $a, b$ and the function $f$ defined on interval $[a, b]$. One such definition was provided by Bernhard Riemann and it assumes $f$ to be bounded on $[a, b]$. I will leave the definition of Riemann integral to the standard textbooks of analysis and focus next on the Fundamental Theorems of Calculus.
First Fundamental Theorem of Calculus: If $f$ is bounded on $[a, b]$ and the Riemann integral $\int_{a}^{b}f(x)\,dx$ exists then the function $F$ defined on $[a, b]$ by $$F(x) = \int_{a}^{x}f(t)\,dt$$ is continuous on $[a, b]$ and $$F'(c) = f(c)$$ for any point $c \in [a, b]$ where $f$ is continuous.
Second Fundamental Theorem of Calculus: If $F$ is differentiable on $[a, b]$ and the derivative $F' = f$ (say) is Riemann integrable on $[a, b]$ then $$F(b) - F(a) = \int_{a}^{b}F'(x)\,dx = \int_{a}^{b}f(x)\,dx$$
Note that the first FTC describes a function $F$ based on a given function $f$ which has some nice properties ($F$ is continuous on $[a, b]$ and differentiable at those points where $f$ is continuous). But this $F$ is not an anti-derivative of $f$ on $[a, b] $ because we are not guaranteed that $F'(x) = f(x)$ for all $x \in [a, b]$. We have $F'(x) = f(x)$ only at those points $x$ at which $f$ is continuous. At points where $f$ is discontinuous the function $F$ may or may not be differentiable.
The second FTC deals with anti-derivatives. It says that if $F$ is anti-derivative of $f$ on $[a, b] $ i.e. $F'(x) = f(x)$ for all $x \in [a, b]$ and further that if $f$ is Riemann integrable on $[a, b]$ then the definite integral $\int_{a}^{b}f(x)\,dx$ can be simply evaluated in terms of the difference between values of anti-derivative (i.e. as $F(b) - F(a)$).
The function $F$ used in first FTC has a different role than the function $F$ of the second FTC and it is useless to think of them as same. Things change drastically when the function $f$ (which is to be integrated) is guaranteed to be continuous on $[a, b]$. When $f$ is continuous then both the FTC get merged into one theorem which we can simply call FTC for continuous functions:
Fundamental Theorem of Calculus for Continuous Functions: If $f$ is continuous on $[a, b]$ then $\int_{a}^{b}f(x)\,dx$ exists and the function $F$ given by $$F(x) = \int_{a}^{x}f(t)\,dt$$ is an anti-derivative of $f$ on $[a, b] $. Moreover if $G$ is any anti-derivative of $f$ on $[a, b]$ then $$\int_{a}^{b}f(x)\,dx = G(b) - G(a)$$
And now you see the connection between the word "anti-derivative" and the integral $$\int_{a}^{x}f(t)\,dt = F(x)$$ The function $F$ is an anti-derivative of $f$ and not necessarily the anti-derivative of $f$. You also remember the fact that a function does not have a unique anti-derivative and two anti-derivatives of the same function differ by a constant and this is the reason for using the constant of integration while calculating indefinite integrals. This is also the reason that I have used a different letter $G$ for a generic anti-derivative in the theorem mentioned above and the letter $F$ denotes a very specific anti-derivative represented in the form of a definite integral.
Thus when you wish to calculate $\int_{2}^{5}x^{2}\,dx$ by the use of anti-derivative $x^{3}/3$ you are just choosing one of the infinitely many anti-derivatives available and it will work as expected. You may wish to choose the specific anti-derivative $\int_{2}^{x}f(t)\,dt = (x^{3}/3) - 8/3$ and this will also work fine.
You can also think in this manner. The anti-derivative $F(x) = \int_{a}^{x}f(t)\,dt$ is a very specific one and has the property $F(a) = 0$. Other anti-derivatives of $f$ will not have this property of vanishing at $a$. And the fundamental theorem says that the choice of anti-derivatives does not matter in evaluating the definite integral.