No. As it turns out, $MN$ and $NM$ must have the same nonzero eigenvalues (although the multiplicities need not agree), so if $(MN)^n = 0$ then $MN$ has only zero eigenvalues, so the same must be true of $NM$, which must therefore have characteristic polynomial $t^n$.
One elegant proof uses the following lemma: in any ring, $1 - xy$ is invertible if and only if $1 - yx$ is invertible. Now use the fact that $\lambda$ is a nonzero eigenvalue of $MN$ if and only if $1 - \frac{MN}{\lambda}$ is not invertible.
Another proof proceeds as follows: let $M, N$ have entries $m_{ij}, n_{ij}$ which are formal variables in a polynomial ring $R = \mathbb{Z}[m_{ij}, n_{ij}]$. Observe that
$$\det(Nt - NMN) = \det(N) \det(t - MN) = \det(t - NM) \det(N).$$
Since $R$ is an integral domain, we conclude that
$$\det(t - MN) = \det(t - NM)$$
as polynomials in $R$. So in fact $MN$ and $NM$ must have the same characteristic polynomial. (Note, however, that the first proof is much more general; among other things, it remains valid in infinitely many dimensions.)