So $f: \mathbb{R} \to \mathbb{R}$ is $n>1$ (or more) times differentiable.
The notation of the first derivative makes perfect "sense" with regard to what's going on:
$$\lim_{h \to 0} \frac{f(x+h) - f(x)}{h} \equiv \frac{df}{dx}$$
The second makes me tilt my head a bit (to no effect):
$$\lim_{h \to 0} \frac{\frac{df}{dx}\big|_{x+h} - \frac{df}{dx}\big|_{x}}{h} = \frac{d}{dx} \frac{df}{dx} = \frac{d^2 f}{dx^2}$$
This notation looks like as if:
$$\frac{d^2 f}{dx^2} = \lim_{h \to 0} \frac{(f(x+h)-f(x))^2}{(x+h)^2-x^2}$$ But I couldn't find any sense in that..
Now, I was told that this notation has complete (more advanced) mathematical sense.
I'd like to know where to look for it.