One useful consequence of $ZFC$ is that the real numbers can be shown to be unique upto isomorphism.
According to wikipedia:
The use of the definite article the in the phrase the hyperreal numbers is somewhat misleading in that there is not a unique ordered field that is referred to in most treatments. However, a 2003 paper by Vladimir Kanovei and Shelah shows that there is a definable, countably saturated (meaning ω-saturated, but not of course countable) elementary extension of the reals, which therefore has a good claim to the title of the hyperreal numbers. Furthermore, the field obtained by the ultrapower construction from the space of all real sequences, is unique up to isomorphism if one assumes the continuum hypothesis.
Unfortunately the page does not give a reference for this result. The result is referenced though in this question. But assuming it correct, presumably this not a good enough reason to settle the continuum hypothesis. But I find the generalisation of uniqueness of the reals upto isomorphism to the hyper-reals here interesting and suggestive.
Q. Why would one want to discount this being of significance in settling the continuum hypothesis in the positive?