First, factor the differential operator on the left. Since $a^2+4ab+4b^2=(a+2b)(a+2b)$, the operator factors as
$$\frac{\partial^2}{\partial t^2} + 4\frac{\partial^2}{\partial x \partial t} + 4\frac{\partial^2}{\partial x^2}=
\left(\frac{\partial }{\partial t }+2\frac{\partial }{\partial x }\right) \left(\frac{\partial }{\partial t }+2\frac{\partial }{\partial x }\right)
$$
The factors are directional derivatives of 1st order. Sadly, they are in the same direction, of the vector $(2,1)$ in the $(x,t)$ plane. This means we have only one characteristic through each point, namely a line of the form $x=2t+C$. The equation is somewhat degenerate, compared to honest hyperbolic equations such as $\frac{\partial^2u}{\partial t^2} + 4\frac{\partial^2 u}{\partial x^2} =0$.
Anyway, we see that along every line of the form $x-2t=C$ the solution is linear (since its second derivative is zero). Hence, we can write down the general solution as
$$u(x,t) = f(x-2t)+t\,g(x-2t)$$
where $f$ and $g$ are arbitrary functions. (Check that this works: the restriction of $u$ to any characteristic is linear.)
If you know the initial value and initial velocity at $t=0$, you can find $f$ and $g$, and with them $u$.