Take the first 6 derivatives "by hand" until the derivatives of the polynomial portion disappear. Now for the rest I give a hint and you modify it to apply it to your problem. Suppose you want to take the derivatives of $y=x^{1/2}$.
you get
$y^{(0)}=x^{1/2}$
$y^{(1)}=1/2 x^{-1/2}$
$y^{(2)}=(1/2)*(-1/2) x^{-3/2}$
$y^{(3)}=(1/2)*(-1/2)*(-3/2) x^{-5/2}$
$y^{(4)}=(1/2)*(-1/2)*(-3/2)*(-5/2) x^{-7/2}$
$\cdots$
$y^{(n)}=(1/2)*(-1/2)*(-3/2)*(-5/2)*\cdots *(1/2-(n-1)) x^{(1/2)-n}$
Now to understand this derivative we need several pieces. (Assume we are looking at derivatives of order $1$ or higher.)
(1) For derivatives of even order product is negative, for odd order it is positive. So this sign can be reproduced by a $(-1)^{n-1}$.
(2) The exponent of $x$ decreases from $-1/2$ to $1/2-n$, i.e. for the $n$-th order it is $-(2n-1)/2$.
(3) The coefficient, aside from the sign, can be written as $(1/2)*(1/2)*(3/2)*(5/2)*\cdots *(2n-3)/2$, where the numerator is the product of all odd numbers from $1$ to $(2n-3)$ and the denominator is $n$ copies of $2$. So the denominator is $2^n$. Now to clean and write the numerator with factorials you can apply the following trick: Multiply and divide by all the numbers that are missing from making a complete factorial in the numerator.
So
$1*3*5*\cdots(2n-3)= \displaystyle{1*2*3*4*5*\cdots*(2n-3)*(2n-2) \over 2*4*6*\cdots*(2n-2)}$
Now notice that you can factor a $2$ from every term in the denominator and write it as $2^{n-1}(n-1)!$. And the numerator is nicely $(2n-2)!$. Putting it all together for $n>0$ we have
$({\sqrt x})^{(n)}= \displaystyle{ (-1)^{n-1} {{(2n-2)!} \over {2^{2n-1}(n-1)!}} x^{-(2n-1)/2}}$
Now to your problem!
To start: $f(x)=x^5+4x^4-4x^{9/2}$. So we just differentiate.
$f'=5x^4+4*4x^3-4*(9/2)x^{7/2}$
$f''=5*4x^3+4*4*3*x^2-4*(9/2)*(7/2)x^{5/2}$
$f'''=5*4*3x^2+4*4*3*2*x-4*(9/2)*(7/2)*(5/2)x^{3/2}$
$f''''=5*4*3*2x+4*4*3*2-4*(9/2)*(7/2)*(5/2)*(3/2)x^{1/2}$
or
$f^{iv}= 5!x+4*4!-4*(9!/4!*2^8)x^{1/2}$
$f^{v}=5!-4*(9!/4!*2^9)x^{-1/2}$
For $n>1$ we have $f^{(n+4)}=-4*(9!/4!*2^8) \displaystyle{ (-1)^{n-1} {{(2n-2)!} \over {2^{2n-1}(n-1)!}} x^{-(2n-1)/2}} $