Let's try to find a polynomial without roots of the form $x^2 + c x + 1$ ( note that $x^2 + c x + d$ has roots if and only if $x^2 + \frac{c}{\sqrt{d}} + 1$ does). So now we need some $c$ that is not of the form $t + \frac{1}{t}$ with $t$ in the field. We'll be using the generator of the field provided by Jyrki. So let $\alpha \in GF(2^4)$ be a root of $x^4 + x + 1 = 0$. We have
$\alpha^4 + \alpha = 1$ so multiplying by $\alpha^5$ we get
$\alpha^9 + \alpha^6 = \alpha^5$. Now raise to the square and get
$\alpha^3 + \alpha^{12} = \alpha^{10}$. (raising again to the square returns to the start).
Now multiply $\alpha + 1 = \alpha^4$ by $\alpha^7$ and get $\alpha^8 + \alpha^7 = \alpha^{11}$. We can now take some squares: $\alpha^1 + \alpha^{14} = \alpha^{7}$, $\alpha^{2} + \alpha^{13} = \alpha^{14}$, $\alpha^{4} + \alpha^{11} = \alpha^{13}$. We still have to check two values: $\alpha^{0} + \alpha^{0} = 0$ and $\alpha^{5} + \alpha^{10}$. The last one is invariant under raising to the square, so it must be $1 = \alpha^{0}$. So here is a little table
\begin{eqnarray}
\alpha^{0} + \alpha ^{0} & =& 0\\
\alpha^{1} + \alpha^{14} & = & \alpha^7\\
\alpha^{2} + \alpha^{13} &=& \alpha^{14}\\
\alpha^{3} + \alpha^{12} & = & \alpha^{10}\\
\alpha^{4} + \alpha^{11}& = & \alpha^{13} \\
\alpha^{5} + \alpha^{10} & = & \alpha^{0}\\
\alpha^{6} + \alpha^{9} & = & \alpha^{5} \\
\alpha^{7} + \alpha^{8} & = & \alpha^{11}
\end{eqnarray}
We can choose for instance $\alpha^{1}$ which is not of the form $t + \frac{1}{t}$, $t \in GF(2^4)$, so $x^2 + \alpha x + 1$ is irreducible.