There is an informal and intuitive proof that yes, the set of degree $n$ (monic) polynomials will have measure $0$ in $\mathbb{R}^n$, based on basic counting.
Here is the idea: a degree $n$ (monic) polynomial is uniquely determined by it's $n$ roots, and vice-versa. Now, count. How many (monic) polynomials have exactly $n-1$ simple roots? Well, I can freely place $n-1$ roots, and the last one has $n-1$ options (place it on top of any of the former roots). Thus, I have $n-1$ real degrees of freedom, and $n-1$ discreet degrees of freedom. This obviously represents disjoint union of $n-1$ copies of $\mathbb{R}^{(n-1)}$, which I will write as $(n-1)*\mathbb{R}^{n-1}$. How many (monic) polynomials have exactly $n-2$ simple roots? Same argument, $(n-2)^2*\mathbb{R}^{n-2}$. In total, you will have $$(n-1)*\mathbb{R}^{n-1} \cup (n-2)^2*\mathbb{R}^{n-2} \cup \dots \cup \mathbb{R} = \cup_{i=1}^{n-1}(n-i)^i\mathbb{R}^{n-i},$$
where all the unions are disjoint. Each of those sets has measure $0$ in $\mathbb{R}^n$ and they are disjoint, so the total measure is $0$.
Intuitively, throw $n$ darts in $\mathbb{R}^n$, you clearly have $0$ probability of darts coinciding.
*Keep in mind that since the coefficients are real, all complex roots appear in pair with their conjugates, so a pair of complex roots still uniquely determines two real degrees of freedom.