I will post this answer just as a complement to Thomas Preu's nice computation above.
Let us write $\Gamma:=\mathrm{Gal}(\mathbf{C}/\mathbf{R})$. Also, let me model $\mathbf{Z}/2\mathbf{Z}$ as $\{\pm 1\}$ -- I will identify them in what follows. As already observed we have a short exact sequence of $\Gamma$-groups
$$1\to \mathbf{C}^\times\to \mathrm{Aut}(\mathbf{G}_{m,\mathbf{C}})\to \mathbf{Z}/2\mathbf{Z}\to 1,$$
where the latter term has trivial $\Gamma$-action and the first the usual $\Gamma$-action. We then know that we get (e.g. see [Serre, §5.5, Proposition 38]) an exact sequence of pointed sets
$$1\to \mathbf{R}^\times\to \mathrm{Aut}(\mathbf{G}_{m,\mathbf{R}})\to \mathbf{Z}/2\mathbf{Z}\to H^1(\Gamma,\mathbf{C}^\times)\to H^1(\Gamma,\mathrm{Aut}(\mathbf{G}_{m,\mathbf{C}}))\to H^1(\Gamma, \mathbf{Z}/2\mathbf{Z}).$$
As already observed by Thomas Preu, by Hilbert's Theorem 90 (e.g. see [Poonen, Proposition 1.3.15]) that $H^1(\Gamma,\mathbf{C}^\times)$ is trivial. Moreover, as $\Gamma$ acts trivially on $\mathbf{Z}/2\mathbf{Z}$ (which is abelian) we have that
$$H^1(\Gamma,\mathbf{Z}/2\mathbf{Z})=Z^1(\Gamma,\mathbf{Z}/2\mathbf{Z})=\mathrm{Hom}(\Gamma,\mathbf{Z}/2\mathbf{Z})=\mathbf{Z}/2\mathbf{Z}.$$
Now, by the definition of exact sequence of pointed sets, the fiber over $1$ of the map
$$H^1(\Gamma,\mathrm{Aut}(\mathbf{G}_{m,\mathbf{C}}))\to H^1(\Gamma, \mathbf{Z}/2\mathbf{Z})\qquad (1)$$
is trivial, and so to understand $H^1(\Gamma,\mathrm{Aut}(\mathbf{G}_{m,\mathbf{C}}))$ it suffices to understand the fiber over the non-trivial element in the map in $(1)$.
That said, let us observe that by [Serre, §5.5, Corollary 2] and our discussion above we know that the fiber of the map in $(1)$ over the non-trivial element can be understood as
$$H^1(\Gamma, {}_\varsigma(\mathbf{C}^\times))/H^0(\Gamma,{}_\varsigma (\mathbf{Z}/2\mathbf{Z}))$$
where $\varsigma$ is any element of $Z^1(\Gamma,\mathrm{Aut}(\mathbf{G}_{m,\mathbf{C}}))$ whose associated cocycle is non-trivial, and where $_\varsigma(-)$ is as in [Serre, §5.3]. Now, explicitly let us take $\varsigma$ corresponding $S^1$ which is given by
$$\varsigma\colon \Gamma\to \mathrm{Aut}(\mathbf{G}_{m,\mathbf{C}})=\mathbf{C}^\times\rtimes (\mathbf{Z}/2\mathbf{Z}),\qquad \sigma\mapsto (1,-1),$$
where $\sigma$ is the complex conjugation map. We can then explicitly compute that $_\varsigma (\mathbf{C}^\times)$ is the group which has the same underlying group, but now for which we have
$$\sigma\cdot \alpha=\sigma(\alpha)^{-1}.$$
Similarly, $_\sigma(\mathbf{Z}/2\mathbf{Z})$ has the same underlying group, and now
$$\sigma\cdot -1= (-1) (-1) (-1)^{-1}=-1,$$
or, in other words, $_\varsigma(\mathbf{Z}/2\mathbf{Z})$ is still just $\mathbf{Z}/2\mathbf{Z}$ with the trivial action.
Now, as $_\varsigma(\mathbf{C}^\times)$ is abelian, and $\Gamma$ is cyclic, we can use Thomas Preu's favorite formula to compute that
$$H^1(\Gamma,{}_\varsigma(\mathbf{C}^\times))=\ker(N)/\mathrm{im}(\Delta).$$
Observe here now that
$$N\colon {}_\varsigma(\mathbf{C}^\times)\to {}_\varsigma(\mathbf{C}^\times),\qquad \alpha\mapsto \sigma(\alpha)^{-1}\alpha,$$
and so the kernel of this map is those $\alpha$ such that $$\sigma(\alpha)=\alpha$$, which is precisely $\mathbf{R}^\times$. On the other hand,
$$\Delta\colon {}_\varsigma(\mathbf{C}^\times)\to {}_\varsigma(\mathbf{C}^\times),\qquad \alpha\mapsto \sigma(\alpha)^{-1}\alpha^{-1},$$
which has image precisely $\mathbf{R}^{>0}$. So, we see that
$$H^1(\Gamma,{}_\varsigma(\mathbf{C})^\times)=\mathbf{R}^\times/\mathbf{R}^{>0}.$$
Now, the action of $_\varsigma(\mathbf{Z}/2\mathbf{Z})$ on this group is by inversion which, is clearly the trivial action, and so all-in-all we see that the fiber over the non-trivial element of the map in $(1)$ is in bijection with
$$H^1(\Gamma,{}_\varsigma(\mathbf{C})^\times)=\mathbf{R}^\times/\mathbf{R}^{>0},$$
which has $2$ elements. Thus, we see that
$$\# H^1(\Gamma,\mathrm{Aut}(\mathbf{G}_{m,\mathbf{C}}))=1+2=3.$$
Remark:
- This was VERY long-winded because I wanted to show all the steps to illustrate the method. That said, in practice I was able to immediately compute the correct answer was 3 using this method. The utility (at least here) is that I never had to actually think about non-abelian group cohomology and, ultimately, could use Thomas Preu's favorite formula.
- Bonus question. This computation of $H^1(\Gamma,{}_\varsigma(\mathbf{C})^\times)$ looks quite similar, at the end, to the calculation of $\mathrm{Br}(\mathbf{R})=H^2(\Gamma,\mathbf{C}^\times)$. On the other hand, the curve $Y$ has smooth compactification a Brauer--Severi variety (a twist of $\mathbf{P}^n_\mathbf{R}$ for some $n$, in this case $n=1$) which is exactly what the Brauer group computes. What is the relationship?
EDIT: Just for fun here is an answer to my second remark.
Let us observe that we have a natural map
$$\mathrm{Twist}(\mathbf{G}_{m,\mathbf{R}})\to \mathrm{Twist}(\mathbf{P}^1_{\mathbf{R}}),\qquad C\mapsto \overline{C},$$
where $\overline{C}$ is the (unique) smooth compactification of $Y$ (e.g. see Tag 0BXX). This map is not an injection though:
$$\overline{S^1}\cong \overline{\mathbf{G}_{m,\mathbf{R}}}\cong \mathbf{P}^1_{\mathbf{R}}.$$
We can model this map of sets group theoretically, and this can actually help us recompute $H^1(\Gamma,\mathrm{Aut}(\mathbf{G}_{m,\mathbf{C}}))$. Namely, we have an injection of $\Gamma$-groups (we can even upgrade this to an embedding of algebraic groups)
$$\mathrm{Aut}(\mathbf{G}_{m,\mathbf{C}})\hookrightarrow \mathrm{Aut}(\mathbf{P}^1_{\mathbf{C}})\qquad \mathbf{(2)}$$
given by sending $f$ to its extension (in the sense of Tag 0BXY) which is still an automorphism by Tag 0BY1. One can explicitly check that the following diagram commutes
$$\begin{matrix}\mathrm{Twist}(\mathbf{G}_{m,\mathbf{R}}) & \to & \mathrm{Twist}(\mathbf{P}^1_{\mathbf{R}})\\ \downarrow & & \downarrow\\ H^1(\Gamma,\mathrm{Aut}(\mathbf{G}_{m,\mathbf{C}})) & \to & H^1(\Gamma,\mathrm{Aut}(\mathbf{P}^1_{\mathbf{C}}))\end{matrix},$$
where the vertical maps are bijections.
We may explicitly describe the image of $\mathbf{(2)}$ as the set of automorphisms $\varphi$ of $\mathbf{P}^1_\mathbf{C}$ such that $\varphi(S)=S$ where $S=\{[1:0],[0:1]\}$. Using the identification of $\Gamma$-groups
$$\mathrm{Aut}(\mathbf{P}^1_\mathbf{C})=\mathrm{PGL}_2(\mathbf{C}),$$
where the latter acts by fractional linear transformations (e.g. see [Mumford, Chapter 0, §5]) we may then make explicitly identify the following $\Gamma$-groups
$$\begin{aligned}\mathrm{Aut}(\mathbf{G}_{m,\mathbf{C}}) &= \left\{\varphi \in \mathrm{Aut}(\mathbf{P}^1_\mathbf{C}):\varphi(S)=S\right\}\\ &=\left\{\begin{pmatrix}a & 0\\ 0 & d\end{pmatrix}\right\}\cup \left\{\begin{pmatrix}0 & b\\ c & 0\end{pmatrix}\right\}\\ &= C(\gamma)\end{aligned},$$
where $\gamma=\left(\begin{smallmatrix}-1 & 0 \\ 0 & 1\end{smallmatrix}\right)$ and $C(\gamma)$ is the centerlizer of $\gamma$ in $\mathrm{PGL}_2(\mathbf{C})$. In particular, observe that we have an identification of $\Gamma$-sets
$$ \mathrm{Aut}(\mathbf{P}^1_{\mathbf{C}})/\mathrm{Aut}(\mathbf{G}_{m,\mathbf{C}})\cong \mathcal{O}_\gamma,$$
where the latter is the conjugacy class of $\gamma$ in $\mathrm{PGL}_2(\mathbf{C})$.
Now, by [Serre, §5.4, Proposition 36] and the above discussion we have exact sequence of pointed sets
$$1\to \mathrm{Aut}(\mathbf{G}_{m,\mathbf{R}})\to \mathrm{Aut}(\mathbf{P}^1_{\mathbf{R}})\to \mathcal{O}_\gamma^\Gamma\to H^1(\Gamma,\mathrm{Aut}(\mathbf{G}_{m,\mathbf{C}}))\to H^1(\Gamma,\mathrm{Aut}(\mathbf{P}^1_{\mathbf{C}})).$$
Now, with the identification of $\Gamma$-groups $\mathrm{Aut}(\mathbf{P}^1_\mathbf{C})=\mathrm{PGL}_2(\mathbf{C})$ and the short exact sequence of $\Gamma$-groups
$$1\to \mathbf{C}^\times\to \mathrm{GL}_2(\mathbf{C})\to \mathrm{PGL}_2(\mathbf{C})\to 1$$
we may use [Serre, §5.7, Proposition 43] to obtain an exact sequence of pointed sets
$$H^1(\Gamma,\mathrm{GL}_2(\mathbf{C}))\to H^1(\Gamma,\mathrm{PGL}_2(\mathbf{C}))\to H^2(\Gamma,\mathbf{C}^\times)=:\mathrm{Br}(\mathbf{R})\cong \mathbf{R}^\times/\mathbf{R}^{>0}.$$
Again by Hilbert's theorem 90 (e.g. in this context see [GS, Example 2.3.4] the first term vanishes, and in fact the map we get an injection $H^1(\Gamma,\mathrm{PGL}_2(\mathbf{C}))\to H^2(\Gamma,\mathbf{C}^\times)$ (see [GS, Theorem 4.4.5]) and in fact must be an isomorphism as the target is isomorphic to $\mathbf{Z}/2\mathbf{Z}$ and the source is non-trivial (as $\mathrm{Twist}(\mathbf{P}^1_\mathbf{R})$ contains the non-trivial element given by $\overline{Y}$). Thus, we see that $H^1(\Gamma,\mathrm{PGL}_2(\mathbf{C}))$ is a two element set.
We see that $\mathbf{G}_m$, corresponding to the trivial cocycle, and $Y$ corresponding to the cocycle
$$\vartheta\colon \Gamma\to \mathrm{Aut}(\mathbf{G}_{m,\mathbf{C}})\subseteq \mathrm{PGL}_2(\mathbf{C}),\qquad \sigma\mapsto \begin{pmatrix}0 & -1\\ 1 & 0\end{pmatrix},$$
form a set of representatives of $H^1(\Gamma,\mathrm{Aut}(\mathbf{G}_{m,\mathbf{C}}))$ which surject onto $H^1(\Gamma,\mathrm{Aut}(\mathbf{P}^1_\mathbf{C}))$. Thus, to determine the size of $H^1(\Gamma,\mathrm{PGL}_2(\mathbf{C}))$ it suffices to determine the fibers over (the images) of each of these cocycles. By [Serre, §5.4, Corollary 2] these fibers are in bijection, respectively, the following sets
$$\mathcal{O}_\gamma^\Gamma/\mathrm{PGL}_2(\mathbf{R}),\qquad \left({}_\vartheta \mathrm{PGL}_2(\mathbf{C})/{}_\vartheta C(\gamma)\right)^\Gamma/({}_\vartheta \mathrm{PGL}_2(\mathbf{C}))^\Gamma.\qquad \mathbf{(3)}$$
It is a fun exercise in linear algebra (NB: I want to thank my friend Alexander Bertoloni Meli for helping me do this exercise), to compute that
$$\mathcal{O}_\gamma=\mathrm{PGL}_2(\mathbf{R})\cdot \gamma\sqcup \mathrm{PGL}_2(\mathbf{R})\cdot \begin{pmatrix}0 & -1\\ 1 & 0\end{pmatrix}$$
The non-triviality is a shadow of the deep notion of geometric conjugacy vs. rational conjugacy. In any case, using this it's easy to compute that the sizes of the sets in $\mathbf{(3)}$ is $2$ and $1$ respectively rederiving the calculation that $\# H^1(\Gamma,\mathrm{Aut}(\mathbf{G}_{m,\mathbf{C}}))=3$.
Finally, an answer to my second remark. From the above we have a natural map
$$H^1(\Gamma, {}_\varsigma(\mathbf{C}^\times))=H^1(\Gamma,{}_\varsigma(\mathbf{C}^\times))/H^0(\Gamma,{}_\varsigma(\mathbf{Z}/2\mathbf{Z}))\hookrightarrow H^1(\Gamma,\mathrm{Aut}(\mathbf{G}_{m,\mathbf{C}}))\to \mathrm{Br}(\mathbf{R}),$$
and this map is a bijection, so it's not very surprising that they produced 'the same computation'.
References:
[GS] Gille, P. and Szamuely, T., 2017. Central simple algebras and Galois cohomology (Vol. 165). Cambridge University Press.
[Mumford] Mumford, D., Fogarty, J. and Kirwan, F., 1994. Geometric invariant theory (Vol. 34). Springer Science & Business Media.
[Poonen] Poonen, B., 2017. Rational points on varieties (Vol. 186). American Mathematical Soc..
[Serre] Serre, J.P., 1994. Cohomologie galoisienne (Vol. 5). Springer Science & Business Media.
it’s not true in general that twists are classified by Galois cohomology — this is true only for classes of varieties that form a ‘stack’ (e.g. quasi-projective varieties — so for affine it’s OK),
you seem to have forgotten the group structure. Namely, it seems that $$\mathrm{Aut}(\mathbb{G}_{m,K})=K^\times\rtimes (\mathbb{Z}/2\mathbb{Z})$$ where $\mathbb{Z}/2\mathbb{Z}$ acts by inversion. Therefore when you use the long exact sequence for group cohomology in the group you seem to get the following terms
Thanks for clarifying the conditions for the types of classification problems amenable to cohomological tools.
And thank you very much for pointing out the non-abelian group structure of $\text{Aut}_{\text{var}}(\mathbb{G}_m\times_kK)$. This is exactly the source of the mistake. I view this as actually answering the first half of my question and not just merely a comment.
As remarked at the end of my own answer, to which you encouraged me, I comment on your approach using the exact sequence. If you have some more details to circumvent the 1-cocycle computation, let me know.
– Thomas Preu Aug 02 '22 at 18:08