$\newcommand{gbin}[1]{\binom{\frac{1}{2}}{#1}}\let\ge\geqslant$Consider the generalised binomial coefficient defined as
$$\gbin{n} := \frac{\left(\frac{1}{2}\right)\left(\frac{1}{2} - 1\right) \cdots \left(\frac{1}{2} - (n - 1)\right)}{n!}$$
for $n \ge 0$. (The value is $1$ when $n = 0$ by usual conventions.)
Is the following true: when $\gbin{n}$ is written in reduced form as $p/q$ with $q > 0$, then the only possible prime factor of $q$ is $2$.
(I have not picked up the question from some source, the reason why I think that the above is actually true is listed below.)
Motivation: If the above is true, then one would be able to define $\gbin{n}$ in any field $k$ whose characteristic is not $2$. Consequently, we would have the identity
$$\sqrt{1 + X} = \sum_{n \ge 0} \gbin{n} X^{n}$$
in the ring $k[\![X]\!]$ just like we have in $\Bbb Q[\![X]\!]$. Using Hensel lifts, we actually do have a square root of $1 + X$ in $k[\![X]\!]$. I believe the "canonical" square root obtained by starting with $1$ should be the one that we get when $k = \Bbb Q$.
Attempt:
Recursively, we have $$\gbin{n + 1} = \frac{\frac{1}{2} - n}{n + 1}\gbin{n}.$$
However, it is not the case that the fraction $\frac{\frac{1}{2} - n}{n + 1}$ is always of the form $a/2^k$ and so this seems useless.
With some more effort, this answer shows that we have $$\gbin{n} = \frac{(-1)^{n-1}}{2^{2n-1}n}\binom{2n-2}{n-1}.$$
This seems more promising as the question is then reduced to showing that
$$n \mid \binom{2n-2}{n-1}.$$