From $F$ we want to construct a field $K$ of order $16 = 2^4.$ Since $F$ is order two then, we want $|K:F| = 4.$ So we would want to find an irreducible polynomial of degree $4$ in $F.$ Then $\frac{F[x]}{p(x)} \cong F[\alpha]$ for a root $\alpha$ of $p(x)$ (in an extension field of $F$ since $p(x)$ is irreducible in $F$). Furthermore, this field will be order $16,$ since it looks like $\{a + b\alpha + c \alpha^2 + d\alpha^3 : a, b, c, d \in F \}.$ So define $K = F[\alpha].$
I am not sure if I can be more specific than this. There is also the possibility that the irreducible polynomial of degree $4$ does not exist? What would one do in this case?