Sorry, I'm not an advanced abstract algebra person, so I haven't seen this situation addressed before. Suppose you abstract the differential operator to just any ol' linear operator $L$ over a field which has the conditions
$L[c_1 u + c_2 v] = c_1 L[u] + c_2L[v]$ and $L[u \cdot v] = v \cdot L[u] + u\cdot L[v]$ and $L[c_1] = 0$ for any constant $c_1.$
Then must such an operator be the differential operator when acting over any field over which such an operator exists?
Purely in the context of a field, you don't necessarily have limits so I don't know if I postulated this question properly, it may be the case that a field is required to be "continuous" in some sense like a Lie group for such an operator to be the differential operator. I think there are conditions over which field elements are unique though too. I never studied topology in-depth, but this may require an extra Hausdorff condition for infinite fields.
So, the answer may end up being "Yes but only over (such and such) a field, otherwise no and here's an example..."