It's been over 15 years since I last did anything with calculus at school, and I've forgotten most things, so please be gentle with your answers. :)
One thing that has always bugged me when getting into more advanced stuff was that the derivative simbols are suddenly manipulated in a way that doesn't make sense to me. For example, let's take the simple equation
$$y=12x^2+24x+45$$
An alternative notation for the same thing would be:
$$f(x)=12x^2+24x+45$$
Here we merely substituted $y$ for $f(x)$. It means the same thing.
If memory serves me right, when we take the first derivative of this function, we have three ways we can write it:
$$y'=24x+24$$ $$f'(x)=24x+24$$ $$\frac{dy}{dx}=24x+24$$
Now, it's this third notation that I'm talking about here. To my understanding the $\frac{dy}{dx}$ doesn't really mean anything by itself. It's just another way to specify that we're talking about a derivative of a function, just like the $'$ in the other two notations.
But then sometimes I come across an equation like this:
$$m\frac{\text{d}^2\mathbf{r}}{\text{d}t^2} = \frac{kqq'}{|\mathbf{r}|^2},$$
And here suddenly the $d$ is being treated like a variable, not to mention the $t$ and... And if memory serves me right, I've seen ever more extreme examples where the fraction $\frac{dy}{dx}$ itself is taken apart and each of the components used as a variable. I think this was popular back in university when I was talking course on differential equations. Barely passed that, half of it didn't make sense, and this was a large part of the reason why. I don't remember why I never asked my teacher about it back then.
So... what does it mean when we start to break the $\frac{dy}{dx}$ apart?