If you want to learn more about the general setting, take a look at this previous answer of mine on Integrating using surface and volume elements. The $|r'(t)|$ and $|r_u \times r_v|$ you mention for line and surface integrals (in $\Bbb{R}^3$) are simply the square root of the determinant Gramian matrix (I leave it to you to verify this).
In your particular case, since $S$ sits inside of some Euclidean space, we can give it the induced Riemannian metric (i.e we can take dot/inner products of vectors which are tangent to the surface $S$). So, here's what we do: first we're going to construct a $3\times 3$ matrix-valued function $G$ as follows:
\begin{align}
G &=
\begin{pmatrix}
\left\langle \frac{\partial r}{\partial u}, \frac{\partial r}{\partial u}\right\rangle
&
\left\langle \frac{\partial r}{\partial u}, \frac{\partial r}{\partial v} \right\rangle
& \left\langle \frac{\partial r}{\partial u}, \frac{\partial r}{\partial t}\right\rangle \\
\left\langle \frac{\partial r}{\partial v}, \frac{\partial r}{\partial u} \right\rangle
&
\left\langle \frac{\partial r}{\partial v}, \frac{\partial r}{\partial v} \right\rangle
&
\left\langle \frac{\partial r}{\partial v}, \frac{\partial r}{\partial t} \right\rangle\\
\left\langle \frac{\partial r}{\partial t}, \frac{\partial r}{\partial u} \right\rangle
&
\left\langle \frac{\partial r}{\partial t}, \frac{\partial r}{\partial v} \right\rangle
&
\left\langle \frac{\partial r}{\partial t}, \frac{\partial r}{\partial t} \right\rangle
\end{pmatrix}
\end{align}
Note that this is a matrix-valued function which means for each $(u,v,t)$, $G(u,v,t)$ is a $3\times 3$-symmetric matrix of numbers obtained by evaluating all the above partial derivatives at the point $(u,v,t)$.
Since the inner product is symmetric: $\langle v,w\rangle = \langle w,v\rangle$ (and in the case of this Euclidean inner product it is just $\sum_i v^iw^i$), it follows that $G$ is a symmetric matrix, so if you have to actually compute a specific example, you only have to compute the upper triangular portion. As a very explicit example, the $(1,3)$ entry of this matrix is
\begin{align}
\left\langle \frac{\partial r}{\partial u}, \frac{\partial r}{\partial t} \right\rangle
&= \dfrac{\partial x}{\partial u}\dfrac{\partial x}{\partial t}
+ \dfrac{\partial y}{\partial u}\dfrac{\partial y}{\partial t}
+ \dfrac{\partial z}{\partial u}\dfrac{\partial z}{\partial t}
+ \dfrac{\partial w}{\partial u}\dfrac{\partial w}{\partial t}.
\end{align}
Now, suppose the parametrization is $r:A\subset \Bbb{R}^3\to r[A] = S\subset\Bbb{R}^4$. Then,
\begin{align}
\int_S f \, dS &= \int_A f\circ r \cdot \sqrt{\det G} \\
&\equiv \int_A f(r(u,v,t)) \cdot \sqrt{\det[G(u,v,t)]}\, du\,dv\,dt.
\end{align}
(where $\equiv$ means "same thing in different notation"). Now, this triple integral over $A\subset \Bbb{R}^3$ can be calculated for example using Fubini's theorem.