We are given that $n>3$ and we have to find the sum of the series given by: $$S=xyz\binom{n}{0}-(x-1)(y-1)(z-1)\binom{n}{1}+...+(-1)^n(x-n)(y-n)(z-n)\binom{n}{n}$$
I figured out that the general term is $$t(r)=(-1)^r(x-r)(y-r)(z-r)\binom{n}{r}$$ but I see no obvious manipulations between the terms nor does any particular series strike my mind.
Can someone provide an approach? Any help would be appreciated.