Let
$$S_n=\displaystyle \sum^{n}_{k=0}(-4)^k\binom{n+k}{2k}\tag{*}$$
This issue can be connected in a natural way to Chebyshev polynomials of the second kind, with explicit expression see Wikipedia article.
$$U_n(x)=\sum_{k=0}^n(-2)^k\binom{n+k+1}{2k+1}(1-x)^k\tag{1}$$
If we take $x=-1$ in (1),
$$U_n(-1)=\sum_{k=0}^n(-4)^k\binom{n+k+1}{2k+1}=(-1)^n (n+1),\tag{2}$$
the second expression for $U_n(-1)$ being a known property (see Remark below).
Now, let us write the same expression as (2), but for $n-1$ instead of $n$ :
$$U_{n-1}(-1)=\sum_{k=0}^{n-1}(-4)^k\binom{n+k}{2k+1}=(-1)^{n-1} (n)\tag{3}$$
Subtracting (3) from (2),
$$\sum_{k=0}^{n-1}(-4)^k\underbrace{\left(\binom{n+k+1}{2k+1}-\binom{n+k}{2k+1}\right)}_{\binom{n+k}{2k}}+(-4)^n=\underbrace{(-1)^n (n+1) - (-1)^{n-1} (n)}_{(-1)^n (2n+1)}\tag{4}$$
(we have used the classical recurrence relationship between binomial coefficients)
It is finished there because (4) expresses the fact that $S_n$ (given by (*)) is :
$$S_n=(-1)^n (2n+1)$$
Remark : Why do we have $U_n(-1)=(-1)^n (n+1)$ ?
It can be easily seen by setting $x=-1$ into the generating function of the $U_n$s :
$$\sum_{n=0}^{\infty}U_n(x)t^n=\dfrac{1}{1-2tx+t^2}$$
giving
$$\dfrac{1}{(1+t)^2}=1-2t+3t^2-4t^3+\cdots$$