If $n\ge 2$ then $$\Bbb S^{n-1}=\left\{\sum_{k=1}^nx_k^2=1\right\}$$ is not homeomorphic to $\Bbb R^n$ because the former is compact and the latter is not. At least I have been explained so when I studied it.
But if $E$ is an infinite dimensional Banach or Hilbert space (over $\Bbb R$ or $\Bbb C$), can we state that $$E\not\cong\{x\in E:\|x\|=1\}?$$