Is there an efficient algorithm to find a group of sets, where all the sets each have the same number of elements and differ from each other by exactly one element, such that the number of unique elements across all sets is minimized?
This question came from wondering how the makers of the card game Spot It! came up with a deck of cards that each differ from each other by only one picture. I posed this question on Code Golf, with some additional detail, and someone suggested I ask the math community.