Let $a,b,c$ be positive integers. Then $f = x^a + y^b + z^c$ is irreducible in $\mathbb{C}[x,y,z]$.
By Gauss, $f$ is irreducible in $\mathbb{C}[x,y,z]$ iff is so in $\mathbb{C}(z)[x,y]$, and so iff in $\mathbb{C}(y, z)[x]$.
So by Eisenstein, it is sufficient to show that $y^b + z^c$ has a single prime factor.
If $b=c$, this factors through $\Pi(y + \zeta ^i z)$ for some primitive root of unity $\zeta$, so ok.
But if $b\neq c$?
This question is related to this post.
Thank you very much!