There are many ways to show that three particular elements of $\Bbb R^3$ form a basis of $\Bbb R^3$.
The basic definition is that they are linearly independent and span $\Bbb R^3$.
To show that $(1,2,3), (0,1,0)$, and $(0,0,1)$ are linearly independent,
assume $a_1(1,2,3)+a_2(0,1,0)+a_3(0,0,1)=(0,0,0)$.
Then $(a_1,2a_1+a_2,3a_1+a_3)=(0,0,0)$ so $(a_1,a_2,a_3)=(0,0,0)$;
that means they are linearly independent.
To show they span $\Bbb R^3$,
note that $(b_1,b_2,b_3)=b_1(1,2,3)+(b_2-2b_1)(0,1,0)+(b_3-3b_1)(0,0,1),$
so any element of $\Bbb R^3$ can be expressed as a linear combination of $(1,2,3), (0,1,0), $ and $(0,0,1)$.
For another method, see the answer to this question, and easily calculate that the determinant
$$\begin{vmatrix} 1 & 0 & 0 \\ 2 & 1 & 0 \\ 3 & 0 & 1 \\ \end{vmatrix}=1\ne0.$$