So the main observation is that there is only one simple module (up to isomorphism) over a simple (finite-dimensional) algebra.
If $R=\mathcal{M}_k(D)$ is simple then all simple modules are isomorphic to a minimal left ideal of $R$, which in turn is isomorphic (as an $R$-module) to $D^k$, see here. Note that $D^k$ is a left $R$-module via standard matrix multiplication.
Now since $\mathcal{M}_n(R)=\mathcal{M}_{kn}(D)$ is simple as well then the same holds for it. So all that you have to prove is that $End_R(D^k)$ is isomorphic to $End_{\mathcal{M}_n(R)}(D^{kn})$.
This can be simplified by proving the following:
Lemma. For any associative unital algebra $D$ and any $n$ we have an isomorphism of algebras $End_{\mathcal{M}_{n}(D)}(D^n)\simeq D^{op}$ where $D^{op}$ is the algebra created from $D$ by reversing multiplication.
Proof. If $f:D^n\to D^n$ is a $\mathcal{M}_n(D)$ endomorphism then
$$f\left(\begin{matrix}
x_1 \\
x_2 \\
\vdots \\
x_n
\end{matrix}\right)=
\left(\begin{matrix}
x_1 & 0 & \cdots & 0 \\
x_2 & 0 & \cdots & 0 \\
\vdots & \vdots & \ddots & \vdots \\
x_n & 0 & \cdots & 0 \\
\end{matrix}\right)
f\left(\begin{matrix}
1 \\
0 \\
\vdots \\
0
\end{matrix}\right)
$$
meaning that $f$ is fully determined by value on $(1,0,\ldots,0)$. So let $f(1,0,\ldots,0)=(y_1,\ldots, y_n)$. It follows that
$$\left(\begin{matrix}
y_1 \\
y_2 \\
\vdots \\
y_n
\end{matrix}\right)=f\left(\begin{matrix}
1 \\
0 \\
\vdots \\
0
\end{matrix}\right)=
\left(\begin{matrix}
1 & 0 & \cdots & 0 \\
0 & 0 & \cdots & 0 \\
\vdots & \vdots & \ddots & \vdots \\
0 & 0 & \cdots & 0 \\
\end{matrix}\right)
f\left(\begin{matrix}
1 \\
0 \\
\vdots \\
0
\end{matrix}\right)
=
\left(\begin{matrix}
1 & 0 & \cdots & 0 \\
0 & 0 & \cdots & 0 \\
\vdots & \vdots & \ddots & \vdots \\
0 & 0 & \cdots & 0 \\
\end{matrix}\right)
\left(\begin{matrix}
y_1 \\
y_2 \\
\vdots \\
y_n
\end{matrix}\right)=
\left(\begin{matrix}
y_1 \\
0 \\
\vdots \\
0
\end{matrix}\right)
$$
and so for $\lambda=y_1$ we have that $f(v)=v \lambda$ for any $v\in D^n$. So it is a scalar multiplication (note that from the right, the order matters), denote it by $f_\lambda$. This shows that
$$\tau:D^{op}\to End_{\mathcal{M}_{n}(D)}(D^n)$$
$$\tau(\lambda)=f_\lambda$$
is a surjective function. I leave as an exercise that it is an injective algebra homomorphism. Note that we have to reverse multiplication in $D$ due to $f_{xy}=f_y\circ f_x$. $\Box$