For topological manifolds, algebraic topology is your best bet (at least if you want a simple proof). For instance, if $X$ is an $n$-manifold and $x\in X$ has Euclidean nbhd $U\ni x$ with homeomorphism $f\colon U\rightarrow \mathbb R^n$, then
$$
H_i(X,X\setminus x) \xleftarrow\sim H_i (U,U\setminus x) \xrightarrow\sim H_i(\mathbb R^n,\mathbb R^n\setminus f(x))
$$
where the map on the left is an excision map (i.e. inclusion) and the map on the right is the induced map $f_*$. We know that $H_i (\mathbb R^n,\mathbb R^n\setminus f(x))\cong \tilde H_{i-1}(S^{n-1})$ ($i>0$) from LES of pair $\mathbb R^n\setminus f(x)\subset\mathbb R^n$ and htpy equivalence $\mathbb R^n\setminus f(x) \simeq S^{n-1}$. In conclusion, for each $x\in X$ and $i > 0$ we find that
$$
H_i (X,X\setminus x)\cong\tilde H_{i-1} (S^{n-1})\cong\begin{cases}\mathbb Z\quad \text{if}\, i=n,\\ 0\quad\text{else.}\end{cases}
$$
This shows that the dimension of a manifold is unique when the manifold is nonempty, since then dimension is determined by local homology at $x\in X$. (Uniqueness of dimension is obviously false for the manifold $X = \emptyset$. Note that this is a manifold.)
Addendum. I think it may be difficult to prove uniqueness of dimension using just the tools of point-set topology. At least, I do not imagine there is an easy proof like the one given above. For instance, it is already difficult to prove that $\mathbb R^m\approx \mathbb R^n\Rightarrow m = n$ without algebraic topology.