There is a great combinatoric interpretation of this problem! Consider a lattice grid. $\binom{2n}{n}$ is the number of ways to get from $(0,0)$ to $(n,n)$ by only taking steps to the rihgt and up: this is because a total of $2n$ steps must be taken, and $n$ of them must be "chosen" to be up, the rest will be to the right.
Now $\binom{n}{k}$ is the number of ways to get from $(0,0)$ to $(n-k,k)$; of $n$ steps, you select $k$ to be up, the rest ($n-k$) will be to the right.
If you want to continue from $(n-k,k)$ to $(n,n)$, there are $n$ steps left in your journey (we've taken $n$, and $2n$ total must be taken). Note that $k$ of these steps must be to the right, and the result will be up. There are $\binom{n}{k}$ ways to make this decision.
Thus there are $\binom{n}{k}$ ways to get to $(n-k,k)$ from the origin then $\binom{n}{k}$ ways to get from there to $(n,n)$. These selections are independent so the total number of paths to $(n,n)$ that pass through $(n-k,k)$ is $\binom{n}{k}^2$.
Every path to $(n,n)$ must pass through $(n-k,k)$ for exactly one value of $k$, so the desired result is gotten by summing over $k$.
Edit: the symmetry used is that the square with vertices $(0,0),(0,n),(n,0),(n,n)$ is symmetric about the line $(a,b)$ for $a+b=n$