Jack D'Aurizio mentioned several sums of the form $\sum_{k=0}^n {2n \choose n+k} (-1)^k k^m $ for non-negative integer $m$ in his answer to my question here.
I quote him here, and I note that each of the sums in the large n limit save for the $m=2$ case looks like $O(1){2n \choose n} $, even though the k-dependence looks quite different:
$$ \sum_{k=0}^{n}\binom{2n}{n+k}(-1)^k = \frac{1}{2}\binom{2n}{n}$$ $$ \sum_{k=0}^{n}\binom{2n}{n+k}(-1)^k k = -\frac{n}{4n-2}\binom{2n}{n} \approx -\frac{1}{4}\binom{2n}{n}$$ $$ \sum_{k=0}^{n}\binom{2n}{n+k}(-1)^k k^2 = 0 $$ $$ \sum_{k=0}^{n}\binom{2n}{n+k}(-1)^k k^3 = \frac{n^2}{2(2n-1)(2n-3)}\binom{2n}{n} \approx \frac{1}{8} \binom{2n}{n}$$
With help from Mathematica, I see the following large-n limit:
$$\sum_{k=1}^{n}\binom{2n}{n+k}(-1)^k \frac{1}{k} \approx -\ln(2)\binom{2n}{n}$$
Since ${2n \choose n}$ increases with n, we can unify all these sums, modulo some O(1) terms, in the form $\sum_{k=1}^n {2n \choose n+k} (-1)^k k^m $. If there's a closed form for all such sums, that would be amazing, but given the increasingly complicated nature of sums of higher powers of k, I think that looking at the large-n limit with its potentially simple form is more fruitful.
I think these sums are pretty neat! Typically one would expect that a decaying dependence on k would shrink the sum, but for large n the magnitude of this $m=-1$ sum looks larger than that of the $m=0$ case, probably because of the interplay with the $(-1)^k$ term. I anticipate that for larger magnitude, negative powers $m$ that the magnitude would decrease. I'm not confident about larger magnitude, positive powers $m$ especially when considering the funny trends from $m=0$ to $m=3$.
Thus my question is whether for all integer powers m the sum $\sum_{k=1}^n {2n \choose n+k} (-1)^k k^m $ takes the form $f(m) {2n \choose n}$ at large n and what the function f(m) might be.