Several open conjectures are widely believed to be true due to strong heuristical evidence. Examples include Goldbach's conjecture , Collatz's conjecture and the Riemann hypothesis.
Are there examples of conjectures that turned out to be false despite of a strong heuristical evdidence to be true ?
I know that there are conjectures with very large smallest counterexamples , but I wonder whether there were additional reasons (except that a counterexample wasn't found for a long time) to believe the conjecture.