Does there exist $d$ and a regular (=polynomial) map from the affine space $\mathbb{A}^d$ to $\mathbb{A}^2$ whose image is exactly the punctured plane $\mathbb{A}^ 2\smallsetminus\{0\}$?
Here the base field is algebraically closed, and of characteristic zero if necessary.
Note that there exist regular maps from the affine space onto the projective line, and more precisely a regular map $\mathbb{A}^1\to\mathbb{A}^2\smallsetminus\{0\}$ (namely $z\mapsto (z,z^2+1)$) whose composite with the quotient map $\mathbb{A}^2\smallsetminus\{0\}\to\mathbb{P}^1$ is surjective, see the MathSE question "Does there exist a regular map $\mathbb{A}^1\to\mathbb{P}^1$ which is surjective?"
If there's a terminology for those varieties admitting a surjective regular map from some affine space, it would help (such varieties are connected, unirational, and all their non-constant regular maps (to $\mathbb{A}^1$) are surjective, excluding, for instance, $\mathbb{A}^1\smallsetminus F$ for $F$ finite nonempty).
Edit Oops, $(a,b,c)\mapsto (a(1+bc)+c,1+bc)$ works (indeed it does not vanish, $(0,-x^{-1},x)\mapsto (x,0)$ for $x\neq 0$ and $(\frac{x+1}{y}-1,1,y-1)\mapsto (x,y)$ for $y\neq 0$. So the question remains only for $d=2$.