In calculus, I would presume that the notion of continuous differentiability is important, which is why we have classes $C^1, C^2,\ldots,C^n$ which are defined in terms of having a continuous $n$th derivative. But why? Why is the derivative being continuous relevant at all?
What is the motivation for defining $C^n$ in terms of not merely being $n$ times differentiable, but $n$ times continuously differentiable? For which (important) theorems in single and multivariable calculus is the hypothesis of continuous differentiability absolutely required?
It is not required for either the fundamental theorem of calculus or integration by substitution, though it is often presented as being such.