To begin with a seemingly random remark, note that
$$4(1-s^2)\gt(2-s)^2\quad\text{for }0\lt s\le{1\over\sqrt2}\approx0.707$$
This is because the inequality simplifies to $s(4-5s)\gt0$, which holds for $0\lt s\lt{4\over5}=0.8$.
Now down to business. As noted by Takahiro Waki in comments, the equation $2^{1-x}+2^{\sqrt{2x-x^2}}=3$ is equivalent to
$$2^{\sin\theta}+2^{\cos\theta}=3$$
with $-{\pi\over2}\le\theta\le{\pi\over2}$. It's easy to see that $2^{\sin\theta}+2^{\cos\theta}\lt3$ for $-{\pi\over2}\le\theta\lt0$, and equality is achieved at $\theta=0$ and $\theta={\pi\over2}$ (corresponding to $x=1$ and $x=0$, respectively). So it remains to show
$$2^{\sin\theta}+2^{\cos\theta}\gt3\quad\text{for }0\lt\theta\lt{\pi\over2}$$
Actually, by the symmetry $\sin({\pi\over2}-\theta)=\cos\theta$ (and vice versa), we need only prove it in the interval $0\lt\theta\le{\pi\over4}$. Now let's abbreviate this to
$$2^s+2^c\gt3$$
where $0\lt s\le{1\over\sqrt2}$ and $c=\sqrt{1-s^2}$. To prove this, let's make clever use of AGM:
$$2^s+2^c=2^s+2^{c-1}+2^{c-1}\ge3\sqrt[3]{2^{s+2c-2}}$$
Thus we need only prove $s+2c-2\gt0$ for $0\lt s\le{1\over\sqrt2}$. But this is straightforward: Since $c\ge0$, we have
$$\begin{align}
s+2c-2\gt0
&\iff2c\gt(2-s)\\
&\iff4c^2\gt(2-s)^2\\
&\iff4(1-s^2)\gt(2-s)^2
\end{align}$$
which takes us back to the obviously now non-random remark at the beginning.