We have a $2N\times2N$ complex block matrix $H$ in the form:
$H=\left(\begin{array}{cc} \alpha & \beta\\ -\beta^{*} & -\alpha^{*} \end{array}\right)$,
where $\alpha$ is a hermitian matrix, $\beta$ is a symmetric matrix, and $\alpha^\ast$ denotes the complex conjugate (but not the conjugate transpose, which is denoted as $\alpha^{\dagger}$) of a matrix $\alpha$.
Is that possible to find a unitary matrix $U$ such that $UHU^{\dagger}=-H$ ?
At first, considering the simplest case where $N=1$, I can use the general form of unitary matrix $U$ to prove that there doesn't exist such $U$. But there is no general form of unitary matrix for higher dimension, so this method fails.
I wonder whether the non-existence is always true for higher dimension?
Discussions for the condition of a matrix $T$ unitary equivalent to $-T$ is also helpful.