This asks whether or not differentiating both sides of an equation is allowed. Which it isn't, however, can you integrate both sides of an equation?
If we have,
$$x^2=x+1$$
Can we apply the integral operator and get,
$${1 \over 3} \cdot x^3 \ |_a^b={1 \over 2} \cdot x+x \ |_a^b$$
Haha, just kidding. That's too easy, I actually mean can we take the anti-derivative of both sides?
$${1 \over 3} \cdot x^3+C_1={1 \over 2} \cdot x+x+C_2$$ $$\Rightarrow {1 \over 3} \cdot x^3-{1 \over 2} \cdot x-x=C$$
Where $C$ is an arbitrary constant. Can doing this ever result in an equation simpler to solve? Perhaps this be used to derive new results? I know that this can be used when the equation is functional, but I'm interested in the cases when it isn't.
Here's one use I came up with,
We have,
$$(1) \quad x^2=x+1$$
$$(2) \quad {1 \over 3} \cdot x^3+C_1={1 \over 2} \cdot x+x+C_2$$ $$\Rightarrow {1 \over 3} \cdot x^3-{1 \over 2} \cdot x-x=C$$
With $C=-\cfrac{5\cdot \sqrt{5}+7}{12}$. Therefore, a root of $(2)$ is ${{\sqrt{5}+1} \over 2}$. This could be done for any order equation where a solution is known. For instance, you could have a quartic equation with known solutions, and then derive a solution to a quantic equation. Assuming you integrate and set $C$ to the right value. This would allow you to find specific solutions of quantic equations, which are not generally solvable.
For a concrete example, consider,
$$(3) \quad (x-1) \cdot (x-2) \cdot (x-3) \cdot (x-4)=0$$
Integrating both sides results in,
$$(4) \quad {{x^5} \over 6}-{{5 \cdot x^4} \over 2}+{{35 \cdot x^3} \over 3}-25 \cdot x^2+24 \cdot x=C$$
If we wish to retain the solution $x=1$ we set $C=251/30$ and then we have,
$$(5) \quad {{x^5} \over 6}-{{5 \cdot x^4} \over 2}+{{35 \cdot x^3} \over 3}-25 \cdot x^2+24 \cdot x-{{251} \over {30}}=0$$
Where we actually know one of the solutions!