Sperner showed in his doctoral thesis [Sperner 1928] that invariance of open sets, invariance of domain and invariance of dimension can be proved already with elementary combinatorial methods alone.
They follow simply from the following theorem of Lebesgue:
A bounded point set $G$ in the $n$-dimensional number space is given, which contains inner points. Given a bounded point set $G$ in the $n$-dimensional number space containing inner points. The points of $G$ be distributed to a finite number of closed sets $M_{i}$ ($i=1,2,3,...,s$), so that every point of $G$ occurs at least in one of the sets $M_{i}$. Then there is at least one point in $G$ which lies in at least $n+1$ sets, if only the $M_{i}$ were chosen sufficiently small.
Sperner proved this theorem of Lebesgue by simple combinatorial methods.
Sperner's lemma can also be used in a proof of Brouwer's fixed-point theorem.
[Sperner 1928] Sperner, Emanuel: Neuer Beweis für die Invarianz der Dimensionszahl und des Gebietes. In: Abh. Math. Sem. Univ. Hamburg. Band 6, 1928, 265–272
Sperner, Emanuel: Gesammelte Werke. Benz, W.; Karzel, H.; Kreuzer , A. (Hrsg.). Heldermann Verlag, Lemgo, Germany, 2005
Sehie Park: Ninety years of the Brouwer Fixed Point Theorem. Vietnam Journal of Mathematics 27 (1999) (3) 187-222
Huang, J.: On the Sperner lemma and ist applications. 2004
Pak, K.: Sperner’s Lemma. Formalized Mathematics 18 (2010) (4) 189-196
Fox, J.: MAT 307: Combinatorics Lecture 3: Sperner's lemma and Brouwer's theorem. 2009
Sperner's Lemma and Brouwer fixed point theorem. 2014
Maliwal, A.: Sperner's Lemma, The Brouwer Fixed Point Theorem, the Kakutani Fixed Point Theorem, and their applications in social sciences. Electronic Theses and Dissertations. 2574. 2016
Anderson, A.: Sperner's Lemma and Brouwer's Fixed Point Theorem. 2021
Encyclopedia of Mathematics: Sperner lemma
Encyclopedia of Mathematics: Brouwer theorem
Wikipdia: Sperner's lemma