Yes, assuming the axiom of choice. (Actually, one needs only the weaker Boolean prime ideal theorem, though it’s not known whether it suffices for the following example.) Vitali’s construction produces an example. For $x,y\in\Bbb R$ write $x\sim y$ if and only if $x-y\in\Bbb Q$; it’s straightforward to verify that $\sim$ is an equivalence relation on $\Bbb R$. Let $A$ contain exactly one member of each $\sim$-equivalence class. (In group-theoretic terms $A$ contains one member of each coset of $\Bbb Q$, where $\Bbb Q$ is viewed as an additive subgroup of $\Bbb R$.)
For $x\in\Bbb R$ let $A+x=\{a+x:a\in A\}$. If $0\ne q\in\Bbb Q$, $A+q$ is disjoint from $A$: if there were some $a\in(A+q)\cap A$, then we’d have $a\in A$ and $a-q\in A$, but $a-q\sim a$, so $A$ cannot contain both $a$ and $a-q$. Thus, $\{A+q:q\in\Bbb Q\}$ is a countable partition of $\Bbb R$.
Clearly the sets $A+q$ for $q\in\Bbb Q$ are homeomorphic, so $A$ can’t be meagre. Suppose that $A$ has the Baire property, and let $U$ be an open set and $M$ a meagre set such that $U\mathrel{\triangle}M=A$. Evidently $U\ne\varnothing$, so there are $a,b\in\Bbb R$ such that $a<b$ and $(a,b)\subseteq U$. Let $J=(a,b)$ and $r=b-a$, and suppose that $x\in\Bbb R$ with $|x|<r$. Then $(J+x)\cap J$ is an open interval, and $M\cup(M+x)$ is meagre, so
$$\big((J+x)\cap J\big)\setminus\big(M\cup(M+x)\big)\ne\varnothing\;.$$
Clearly $$(A+x)\cap A\supseteq\big((J+x)\cap J\big)\setminus\big(M\cup(M+x)\big)\;,$$ so $(A+x)\cap A\ne\varnothing$ whenever $|x|<r$. Now let $x$ be a positive rational less than $r$ to get a contradiction.
There are models of $\mathsf{ZF}$, however, in which every subset of $\Bbb R$ has the Baire property; obviously $\mathsf{AC}$ fails in such models.