The question is unclear, since as Derek Holt mentioned, "solvable word problem" has not been defined. If you have a presentation with a sequence of generators, you can ask two questions:
1) whether this group endowed with this generating family has a solvable word problem
2) whether this group is isomorphic to a computable group (i.e. is finite or isomorphic to $\mathbf{N}$ endowed with a computable law; this also means that it admits a generating family (maybe not the initial one) for which the word problem is solvable.
For instance, as a variation of Ferov's answer: let $K\subset\mathbf{N}$ be a recursively enumerable, non-recursive set.
a) Consider the group $\langle x_1,x_2,\dots\mid x_k=1 \forall k\in K\rangle$
then the word problem is not solvable with respect to this generating family. But of course this group is free abelian of countable rank, hence has solvable word problem with respect to a better choice of generating family!
b) If instead we consider, the group $$\langle x_1,x_2,\dots\mid x_j^j=1 \forall j\in\mathbf{N},\;x_k=1\forall k\in K\rangle,$$ then it is isomorphic to $A_K=\bigoplus_{k\in\mathbf{N}-K}\mathbf{Z}/k\mathbf{Z}$. Now assume that $K$ contains all non-primes: then if $A_K$ were computable, we could enumerate all the orders of torsion elements of $A_K$, which is exactly $\mathbf{N}-K$, a contradiction.