I always was apprehensive about defining custom keybindings because it's so easy to run into conflicts. And lo, when I finally bound org-agenda because it's just too useful not to have it bound, I run into conflict with c++-mode a day later.
Is there such a thing as reserved combination of keys to use as a prefix for user-specified bindings or are we forced to play roulette with every key-binding that starts C-c?