In $\{wxw^R|w,x\in\{0,1\}^+\}$, we're free to choose $x$ to be any non-empty sequence, including all but the first and last characters of $wxw^R$. So we might as well limit $w$ to be a single symbol; it won't change anything.
So $L$ is exactly the same as $L' = \{axa|a\in\{0,1\}\land x\in\{0,1\}^+\}$ which is evidently regular.
Here's a more formal proof, in case the above was too telegraphic. Suppose we have
$$L = \{wxw^R|w,x\in\{0,1\}^+\}$$
Now:
$$\{0,1\}^+ \equiv \{0,1\} \cup \{aw | a \in \{0,1\} \land w \in \{0,1\}^+$$
which just says that $w^+$ is either exactly one symbol or one symbol concatenated with $w^+$. Also observe that if $a$ is a symbol and $w$ is a sequence of symbols, then $a^R\equiv a$ and $(aw)^R\equiv w^Ra$. So we can rewrite $L$ as a union:
$$L = \{axa|a\in\{0,1\}\land x\in\{0,1\}^+\} \cup \{awxw^Ra|a\in\{0,1\}\land w,x\in\{0,1\}^+\}$$
Now, looking at the two sets in that union, we can see that
$$\{awxw^Ra|a\in\{0,1\}\land w,x\in\{0,1\}^+\} \subset \{axa|a\in\{0,1\}\land x\in\{0,1\}^+\}$$
because
$$\{wxw^R|w,x\in\{0,1\}^+\} \subset \{0,1\}^+$$
and since for any sets $A$ and $B$
$$B \subset A \implies A = A \cup B$$
We can simplify the definition of $L$ to
$$L = \{axa|a\in\{0,1\}\land x\in\{0,1\}^+\}$$
which is clearly a regular language.