It is not quite difficult to understand the idea of differential cryptanalysis applied to a standalone block cipher. The method investigates, how differences of plaintext evolve while going through rounds of the cipher.
But several sources mention the analysis of a block cipher in a mode of operation. But, for instance, "Differential Cryptanalysis of Data Encryption Standard" by Biham and Shamir just mentions, that DES in all standardized modes remains secure. The authors give no idea, how to perform such analysis.
The question is: what is the idea behind differential cryptanalysis of a block cipher in a mode of operation? There are no rounds involved, they are hidden in the cipher. So, what is the process, during which the differences evolution is investigated?