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Generally are there any distinguishable patterns you look find in the opening that you recognize as weak, or exploitable. Or generally any openings that provide the over-bearing sense of duty on a piece?

TheAutomaton
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  • Chess is too complex of a game to be generalizable in that way. Which squares are key and which pieces are most important are all context dependent, i.e. depend on the intricate details of a given position. If you have a specific opening in mind, that would help to make the question less vague and you'd then probably receive actually useful answers. – user929304 Jan 24 '18 at 10:03

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Prior to castling, f2/f7 are the most exploitable squares in the game, because they are defended by only one piece: the king. That's why so many king-stuck-in-the-center games are rounded off by a piece sacrificing itself on those squares.

On the queenside, the c2 and c7 squares also have problems, because of a tactical sequence like this:

1. Bf1-b5+ Qb6xb5
2. Nd5-c7 (forking the queen with either a king on e8, or a rook on a8)

But these tactics happen less often than tactics on f2-f7, because the queen is usually a better defender than the king.

mmyoung77
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In the French Defense, Tarrash variation, `1.e4,e6 2.d4,d5 3.Nd2, Nf6 4.e5,Nfd7 White must carefully guard d4 and e5 as Black will play c5, & Nc6, & possibly Qb6. One scheme for White is Bd3 & Ndf3 & Ne2 & c3 (not necessarily in that order) & be willing to play ef6 if Black plays f6 (which can result in a weak Black pawn on e6).