Suppose that $A$ is an $m \times n$ matrix. The $(i, j)$-entry of $A$ is denoted as $[A]_{i,j}$.
Suppose that $A$ is an $m \times n$ matrix. Suppose that $i_1$, $i_2$, $\dots$, $i_s$ are distinct integers less than or equal to $m$, and that $j_1$, $j_2$, $\dots$, $j_t$ are distinct integers less than or equal to $n$. The matrix obtained from $A$ by removing rows $i_1$, $i_2$, $\dots$, $i_s$ and columns $j_1$, $j_2$, $\dots$, $j_t$ is denoted as $A({i_1,\dots,i_s}|{j_1,\dots,j_t})$.
Determinants are defined here.
I will prove, by directly appealing to the definition, that $$ \begin{aligned} \det {(A)} = \sum_{1 \leq i < k \leq n} {\det { \begin{bmatrix} [A]_{i,1} & [A]_{i,2} \\ [A]_{k,1} & [A]_{k,2} \\ \end{bmatrix} } (-1)^{i+k+1+2} \det {(A(i,k|1,2))}}. \end{aligned} $$ for any $n \times n$ matrix $A$ (in which $n > 2$).
Note that the result is simply an easy corollary of the generalized Laplace expansion. It will be useful in a proof of the alternating property of $\det$ and in a proof of the antisymmetric property of $\det$.