There is a general trick for functions with symmetry which can be used here if you allow for non-integer continuation of the factorial function (which one should I think). Let us denote:
$\binom{n}{k} = F_{n}(k)$.
The binomial identity give us:
$ F_{n}(k) = F_{n}(n-k)$.
Taking the derivative of both sides gives:
$F'_{n}(k)=-F'_{n}(n-k)$.
Now assuming that only one extrema exists at $k = \bar{k}$ then $F'(\bar{k}) = 0$. We then have:
$F'(n-\bar{k}) = 0 \rightarrow \bar{k} = (n-\bar{k})$
Giving, $\bar{k} = n/2$. Translating to integers this gives the floor and ceil of (n/2) as the solutions.
Of course I had to assume there was only extrema of the binomial coefficient. One can see this by graphing the binomial coefficient but here is a sketchy outline of how it can be done with these functions.
From the requirements, $F_{n}(0) = F_{n} (n) = 1$ and $F_{n}(k)>1$, we know that the number of extrema must be odd. From the binomial identity,
$F_{n}(k+1) = \frac{n-k}{k+1} F_{n}(k)$,
one can show that the derivative an integer step to the left/right of the extremal point is positive/negative. This shows that the only extremal points allowed are concave. Since one can't have more than one extrema without having convex extrema, we conclude that there is only one extrema.