Start with a commutative unital ring $X$, and consider the collection $\mathcal{L}$ of all rings $R$ such that there exists a multiplicative subset $S \subset R$ where $R\left[S^{-1}\right] \cong X$. Is there necessarily an $R \in \mathcal{L}$ such that the only non-units of $R$ are $\pm 1$? I.e. is there a "best" un-localization of $X$? And is this $R$ going to be unique in any sense? Is every other ring $R' \in \mathcal{L}$ going to be some localization of $R$ too? Generally what is the structure of $\mathcal{L}$ for a given ring $X$? Is this question more interesting if we reformulate it for not-necessarily-unital rings instead?
Note that I'm aware this might be a poor question; I'm very much spit-balling ideas I've never considered before, this sort of "inverse problem" for localization, to see if it's meaningful and if folks have thought about it before.