If you want to abstain abuse of notation, you can proceed as follows. Compute the limit the ratio for $x \to \infty$:
$\qquad\begin{align*}
\lim_{x \to \infty} \frac{x^4 + x^2 + 1}{x^4 + 1}
&= \lim_{x \to \infty} \frac{1 + \frac{1}{x^2} + \frac{1}{x^4}}{1 + \frac{1}{x^4}} \\
&= \frac{\lim_{x \to \infty} 1 + \lim_{x \to \infty} \frac{1}{x^2} + \lim_{x \to \infty} \frac{1}{x^4}}{\lim_{x \to \infty} 1 + \lim_{x \to \infty} \frac{1}{x^4}} \\
&= \frac{1 + 0 + 0}{1 + 0} \\
&= 1
\end{align*}$
Note that in the first step is just fraction arithmetics and the second uses rules of calculations with limits; check for yourself that these are valid steps (in particular, all the "small" limits are finite).
Now, by definition of $\sim$ (asymptotic equivalence) we get that $x^4 + x^2 + 1 \sim x^4 + 1$ which implies
- $x^4 + x^2 + 1 \in \Theta(x^4 + 1)$,
- $x^4 + x^2 + 1 \in O(x^4 + 1)$ and
- $x^4 + x^2 + 1 \in \Omega(x^4 + 1)$.
Of course, this calculation generalises to all polynomials: for $P$ a polynomial of degree $k$ with positive dominant coefficient $a_k$ we have that $P(x) \sim a_k x^k$ holds.
Your second example works similarly but you get $0$ as limit; this, by definition, implies $x^3 + 5\log x \in o(x^4 + 1)$.